Increasingly though I notice that more and more people are breaking from this practice whether through test learnings or just asthetic decisions. An example being Aviva.co.uk .As you can see below their landing page for car insurance aligns much of it's content to the left of the page. Having become comfortable with placing the onward journey point at the bottom right this just jars. Having said that it's important to challenge the norms to see what resonates with the customer. I may have to test this layout myself to check we're not missing a trick.
In the meantime here's a mock-up of an alternative design I would test based on established findings.